Chaga (Inonotus obliquus)
A Premium Wild-Harvested Medicinal Fungus
chaga
Chaga (Inonotus obliquus), often called the “King of Medicinal Mushrooms,” is highly valued for its powerful antioxidant and immur-boosting properties. Traditionally used in Siberian and Chinese medicine. Chaga supports immune health, combats inflammation and promotes overall vitality. At Herbal Treasure, we wild-harvest chaga from the pristine forests of Russia and Northern China, ensuring the highest quality and bioactivity. We hold certified permits for wild harvesting, adhering to sustainable practices to preserve the natural environment. After collection, the Chaga undergoes careful selection, cleaning, drying and cold storage to maintain its potency and ensure optimal quality.
Benefits and Advantages
Immune System Support
Activates immune cells and enhances the body’s ability to fight infections.
Powerful Antioxidant Protection
Rich in polyphenols and superoxide dismutase (SOD), protecting cells from oxidative stress.
Anti-Inflammatory Effects
Reduces chronic inflammation and supports overall wellness.
Digestive Health
Supports gut health and alleviates gastrointestinal discomfort.
Liver Detoxification and Health
Aids in the body’s detoxification process and promotes healthy liver function.
Anti-Aging and Vitality Support
Boosts energy levels and helps slow the effects of cellular aging.
Scientific Harvesting and Rigorous Quality Control
Harvest Timing Control
Chaga is collected during the ideal growth stage to ensure peak bioactivity.
Processing and Storage
After drying, Chaga is stored in cold storage to maintain quality. Powder customization options range from 80 to 1000 mesh, tailored to customer needs.
Strict Quality Inspection and Certifications
Each batch undergoes rigorous testing for heavy metals, pesticide residues, and microbial content, ensuring compliance with cGMP, FSSC, EU & US Organic standards.
Advanced Extraction Process of Chaga Mushroom Extracts
At Herbal Treasure, we utilize patented jet stream cell-wall breaking technology along with advanced concentration methods to maximize the bioactivity of Chaga extracts. Our low-temperature and normal-pressure extraction preserves the potency of essential compounds throughout the process.
Sustainable Wild Harvesting and Scientific Management
At Herbal Treasure, we responsibly harvest Chaga mushrooms from forests in Russia and Northern China. We follow sustainable practices to ensure environmental balance and maintain our wild harvesting certifications. After collection, the Chaga mushrooms undergo a meticulous post-harvest process, including:
- Careful Selection: Only mature and high-quality Chaga specimens are chosen.
- Cleaning: Chaga is thoroughly cleaned to remove any dirt or debris.
- Drying: Low-temperature drying ensures bioactive compounds remain intact.
- Cold Storage: Chaga is stored in cold conditions to preserve freshness and potency until further processing.
What Makes Our Process Unique?
Choose Herbal Treasure’s Chaga extracts to provide your customers with premium quality products, backed by sustainable wild harvesting practices, advanced extraction technology, and rigorous quality control.
Academic Research on Inonotus obliquus (Chaga) Efficacy
1. Potent Anticancer Effects & Mechanisms
A 2024 Scientific Reports study found Chaga extract inhibited oral cancer (HSC‑4 cells) proliferation in a dose-dependent way. Mechanisms included cell-cycle arrest via STAT3 suppression, reduced glycolysis and mitochondrial potential, and induction of autophagy-mediated apoptosis through AMPK, p38 MAPK, and NF‑κB pathways nature.com+1nature.com+1.
In dog bladder cancer organoids and other tumor cell lines, Chaga demonstrated cell-cycle arrest and apoptosis induction through its triterpenoids, polysaccharides, phenolics, and ergosterol peroxide frontiersin.org+1verywellhealth.com+1.
2. Strong Anti-Inflammatory & Immunomodulatory Properties
Polysaccharides in Chaga (IOPS) have been shown to modulate the immune response, reduce pro-inflammatory cytokines (IL-6, TNF‑α), and suppress COX‑2 in macrophages esmed.org+1frontiersin.org+1.
Beta-glucan fractions modulate immunity, exhibit antioxidant and anti-inflammatory activities cell.com+12frontiersin.org+12mdpi.com+12.
3. Antioxidant, Metabolic, and Cardioprotective Actions
Chaga extract protects liver tissue against chemically induced oxidative damage realsimple.com+4webmd.com+4wired.com+4.
It lowers LDL cholesterol, triglycerides, and boosts antioxidant levels in animal and small human studies health.clevelandclinic.org.
Safety & Quality Considerations
High oxalate intake from Chaga may cause kidney issues in susceptible individuals health.clevelandclinic.org+13journals.lww.com+13frontiersin.org+13.
Lack of standardized clinical trials means health claims remain preliminary wired.com+5en.wikipedia.org+5en.wikipedia.org+5.
Key Bioactive Constituents
Polysaccharides (IOPS): anticancer, anti-inflammatory (macrophage IL‑6, TNF‑α suppression) frontiersin.org+1mdpi.com+1.
Triterpenoids (e.g., inotodiol): influence dendritic cell maturation; seen as complementary in cancer therapies researchgate.net.
Phenolic compounds (syringic acid, protocatechuic acid): contribute to anticancer effects via metabolic interference nature.com+1nature.com+1.
Summary Table
| Therapeutic Area | Evidence & Mechanism |
|---|---|
| Cancer inhibition | Cell-cycle arrest, apoptosis via STAT3, AMPK, NF‑κB pathways |
| Anti‑inflammation | ↓ IL‑6, TNF‑α in macrophages; COX‑2 inhibition |
| Antioxidant / cardio | Liver protection, LDL/triglyceride reduction, ↑ antioxidant enzymes |
| Safety | Kidney risk with high oxalate; variability in product quality and clinical evidence |
References
Jung et al. (2024), “Chaga mushroom extract suppresses oral cancer cell growth via…STAT3, AMPK, p38 MAPK, NF‑κB” – Sci Rep. mskcc.org+2nature.com+2nature.com+2en.wikipedia.org
Elbadawy et al. (2023), “Anti‑tumor potentials of Chaga mushroom extract on dog bladder cancer organoids” – in vitro & in vivo evidence esmed.org+13frontiersin.org+13mdpi.com+13
Anti‑inflammatory study (2023), Chaga polysaccharides reduce IL‑6, TNF‑α, COX‑2 in macrophages zh.wikipedia.org
Liver and cardiometabolic: protection from oxidative injury; lower LDL and triglycerides, raise antioxidants health.clevelandclinic.org+1nature.com+1
Safety note: oxalate nephropathy risk and need for more human trials en.wikipedia.org+2journals.lww.com+2realsimple.com+2
