Maitake Mushroom
A Premium Medicinal Fungus
Maitake Mushroom
Maitake (Grifola frondosa), also known as the “Dancing Mushroom,” has been valued in Asian medicine for its powerful health benefits. Recognized for its immune-boosting properties, blood sugar requlation, and cardiovascular support, Maitake is a popular ingredient in health supplement and functional foods. At Herbal Treasure, we cultivate Maitake in advanced greenhouses, ensuring optimal growing conditions to deliver high-quality Maitake enriched with key bioactive compounds, such as polysaccharides, beta-glucans, and D-fraction.
Benefits and Advantages
Immune System Support
Stimulates immune cells, such as macrophages and T-cells, enhancing the body's ability to fight infections and diseases.
Blood Sugar Regulation
Helps lower blood sugar levels, improving insulin sensitivity and supporting metabolic health.
Cardiovascular Health
Reduces cholesterol, improves blood circulation, and helps prevent heart disease.
Anti-Inflammatory and Antioxidant Properties
Neutralizes free radicals, reduces inflammation, and promotes cellular health.
Weight Management Support
Regulates lipid metabolism and helps control body weight.
Anti-Fatigue and Recovery
Increases energy levels and aids in recovery after physical activity or illness.
Scientific Harvesting And Rigorous Quality Control
Harvest Timing Control
Hand-harvested when fully mature to ensure maximum levels of active compounds.
Processing and Storage
Maitake is dried at low temperatures (40-50°C) to preserve bioactive compounds and enhance bioavailability. We also apply low-temperature sterilization without irradiation to maintain the mushroom’s natural integrity. Powder can be customized to 80 to 1000 mesh based on customer needs.
Strict Quality Inspection and Certifications
Each batch undergoes thorough testing for heavy metals, pesticides, and microbial content, ensuring compliance with cGMP, FSSC, EU & US Organic standards.
Advanced Extraction Process of Maitake Mushroom Extracts
At Herbal Treasure, we use patented jet stream cell-wall breaking technology combined with advanced concentration techniques to maximize the potency of Maitake extracts. Our low-temperature and normal-pressure extraction ensures that all bioactive compounds retain their full therapeutic efficacy.
Standardized Production and Scientific Management
At Herbal Treasure, we cultivate Maitake mushrooms in greenhouses using carefully selected premium strains to ensure high bioactivity. Our standardized production system guarantees consistent quality and uniform standards across every batch. Our expert cultivation team provides 24/7 monitoring, managing temperature, humidity, and light conditions with precision. This optimized environment promotes the accumulation of key compounds like polysaccharides, beta-glucans, and D-fraction, delivering potent therapeutic properties for health applications.
What Makes Our Process Unique?
Choose Herbal Treasure’s Maitake extracts to provide your customers with premium quality products, backed by cutting-edge cultivation, extraction, and rigorous quality management.
Scientific Research on Grifola frondosa (Maitake Mushroom)
1. Immune-Modulating β‑Glucan (D‑Fraction)
Maitake’s D‑Fraction, a protein-bound β‑glucan extract, has demonstrated powerful immunomodulatory and antitumor effects in multiple studies:
Breast cancer cells: Eliana Alonso et al. (2013) showed D‑Fraction activates SPARC and IGFBP-5 gene expression, reducing proliferation and malignancy in MCF‑7 cells discoverymedicine.com+15researchgate.net+15pmc.ncbi.nlm.nih.gov+15.
TNBC (MDA‑MB‑231): In vitro, D‑Fraction induced apoptosis, suppressed PI3K/Akt and ERK signaling, reduced migration/invasion, and enhanced E‑cadherin expression; in mice, it slowed tumor growth and lung metastasis oncotarget.com+1researchgate.net+1.
2. Preclinical & Early Clinical Evidence
Phase I/II trial: Maitake polysaccharide extracts showed immunomodulatory potential in cancer patients herbalreality.com+2pmc.ncbi.nlm.nih.gov+2ascopubs.org+2.
Radiation protection and immune enhancement: Yan et al. (2010) found Maitake polysaccharides improved immune recovery and survival in irradiated mice pmc.ncbi.nlm.nih.gov+15discoverymedicine.com+15atm.amegroups.org+15.
Combination therapies: D‑Fraction enhances NK-cell activity and cytokine production in animals and early clinical settings bmcresnotes.biomedcentral.com+6researchgate.net+6oncotarget.com+6.
3. Structural & Cultivation Insights
Figures include:
The molecular diagram of D‑Fraction glucans (β‑1,3/1,6 branched chains) mdpi.com+1pmc.ncbi.nlm.nih.gov+1.
Photos showing Maitake fruiting bodies and culture development discoverymedicine.com+15researchgate.net+15atm.amegroups.org+15.
Summary Table
| Benefit Area | Evidence & Mechanism |
|---|---|
| Antitumor | Induces apoptosis, gene activation (SPARC, IGFBP-5), inhibits invasion and metastasis |
| Immune Enhancement | Stimulates NK cells, T-cells, cytokines; protects against radiation damage |
| Bioactive Compounds | D‑Fraction: β‑glucan–protein complex with strong bioactivity; structure defined by β‑1,3/1,6 chain branching |
| Human Studies | Early-phase trials show immunomodulation; animal studies support survival benefits |
Key References
Alonso et al., J. Med. Food (2013): Maitake D‑Fraction activates SPARC and IGFBP in breast cancer models verywellhealth.com+15researchgate.net+15bmcresnotes.biomedcentral.com+15discoverymedicine.commdpi.comascopubs.org+1pmc.ncbi.nlm.nih.gov+1.
Phase I/II immunomodulatory trial with Maitake polysaccharide extract atm.amegroups.org+4pmc.ncbi.nlm.nih.gov+4ascopubs.org+4.
Yan et al., 2010: Enhanced immune recovery and survival post-radiation discoverymedicine.com.
D‑Fraction activation of NK cells and cytokine modulation in vivo and in vitro .
