Shiitake Mushroom
A Premium Medicinal and Culinary Fungus
Shiitake Mushroom
Shitake (Lentinula edodes) is both a prized culinary mushrom and a well-regarded medicinal ingredient in tradional Asian medicine. Known for its ability to boost immunity, reduce inflammation, and supbort cardiovascular health, Shiitake is widely used in health supplements and functional foods. At Herbal Treasure,we cultivate shiitake mushrooms using log-based cultivation (on hardwood), replicating their natural environment to ensure optimal growth and high bioactivity.
Benefits and Advantages
Immune System Support
Activates immune cells, enhancing the body’s ability to fight infections.
Cardiovascular Health
Lowers cholesterol levels and improves blood circulation.
Anti-Inflammatory and Antioxidant Properties
Reduces inflammation and protects cells from oxidative damage.
Gut Health and Digestion
Promotes a healthy gut microbiome and supports digestive function.
Energy and Vitality
Increases stamina and helps reduce fatigue.
Skin Health
Promotes collagen production, improving skin elasticity and appearance.

Scientific Harvesting And Rigorous Quality Control
Ensuring High-Quality and High-Activity Reishi. We operate over 500 acres of organic cultivation base where we employ forest-floor simulated wild cultivation, closely replicating the natural environment to optimize Reishi’s growth conditions:
Harvest Timing Control
Shiitake mushrooms are hand-harvested at peak maturity, ensuring the highest levels of bioactive compounds.
Processing and Storage
After harvesting, Shiitake undergoes low-temperature drying (40-50°C) to preserve active ingredients and enhance flavor. Low-temperature sterilization without irradiation maintains the natural integrity of the product. Powder can be customized to 80 to 1000 mesh based on customer requirements.
Strict Quality Inspection and Certifications
Each batch is rigorously tested for heavy metals, pesticide residues, and microbial content, ensuring compliance with cGMP, FSSC, EU & US Organic standards.
Advanced Extraction Process of Shiitake Mushroom Extracts
At Herbal Treasure, we employ patented jet stream cell-wall breaking technology alongside advanced concentration techniques to maximize the bioactivity of Shiitake extracts. Our low-temperature and normal-pressure extraction ensures that beneficial compounds are preserved throughout the process.

Standardized Production and Scientific Management
At Herbal Treasure, we cultivate Shiitake mushrooms using hardwood logs (primarily oak), which provide essential nutrients to stimulate the production of lentinan, polysaccharides, and beta-glucans. Our expert team provides whole day of environmental conditions, such as temperature, humidity, and airflow, to ensure that every batch meets consistent quality standards. This log-based cultivation method enhances the flavor, texture, and medicinal properties of Shiitake, ensuring superior health benefits.
What Makes Our Process Unique?
Choose Herbal Treasure’s Shiitake extracts to provide your customers with premium quality products, supported by advanced cultivation, extraction technology, and rigorous quality control.
Retains the potency of heat-sensitive compounds.
Breaks down tough fungal cell walls to improve extraction efficiency and bioavailability.
Filters out impurities while retaining active compounds, resulting in a high-purity extract.
Ensures consistent quality and effectiveness across every batch.
Scientific Research on Lentinula edodes (Shiitake Mushroom)

Immunomodulation & Anti-inflammatory Effects
A crossover, placebo-controlled trial in healthy elderly participants found that supplementation with soluble β‑glucans derived from shiitake mycelium led to significant improvements in immune markers, including increased NK cell activity and T-cell proliferation nature.com+9ascopost.com+9researchgate.net+9mdpi.com.
Preclinical studies show that β‑glucans reduce pro-inflammatory markers (e.g., CRP) and mitigate the effects of inhaled endotoxins, supporting use in respiratory inflammation .
Support for Innate Immune Function in Healthy Adults
In a 2015 randomized dietary intervention, healthy adults who consumed dried shiitake daily exhibited enhanced γδ‑T cell activation and higher salivary immunoglobulin A (sIgA), suggesting improved mucosal immunity researchgate.net.
Cholesterol & Cardiometabolic Benefits
A phase II clinical trial is evaluating shiitake-based bars’ effects on cholesterol levels and oxidative stress, reflecting interest in dyslipidemia management using whole mushroom products sciencedirect.com+2clinicaltrials.gov+2health.com+2.
β‑glucans from shiitake (and other sources) have been widely linked to cholesterol reduction and antioxidant effects, aligning with FDA health claims on β‑glucans at 3 g/day pmc.ncbi.nlm.nih.gov.
Summary Table
Benefit Area | Mechanism & Evidence |
---|---|
Immune function | Boosts NK/T-cell activity, enhances sIgA, modulates inflammation |
Respiratory support | Protects against endotoxin-induced blood changes |
Heart & metabolism | Supports cholesterol control, reduces oxidative stress |
References for Direct Use
Gaullier JM et al., Int. J. Med. Mushrooms (2011): Soluble β‑glucan crossover trial in elderly, improved NK/T-cell immunity tandfonline.com+14mdpi.com+14researchgate.net+14.
Dai X et al., 2015 randomized dietary study: Daily dried shiitake enhances γδ‑T cell activation and sIgA clinicaltrials.gov+4researchgate.net+4ascopost.com+4.
PMCID PMC10311971 (2023): Shiitake β‑glucan attenuates LPS-induced blood changes pmc.ncbi.nlm.nih.gov.
ClinicalTrials.gov NCT04186780: Phase II trial on shiitake bars for cholesterol and oxidative stress clinicaltrials.gov.
EFSA/FDA β‑glucan reports: Mechanistic review on β‑glucans, their absorption, and cholesterol-lowering effects .
Cassileth BR, Cancer Network (2011): Overview of shiitake’s medicinal and dietary value it.wikipedia.org+5ascopost.com+5cancernetwork.com+5.
Wikipedia “Shiitake”: Notes on rare dermatitis and traditional usage sciencedirect.com+15en.wikipedia.org+15cancernetwork.com+15.